Sanofi Eyes Breakthrough with Dren Bio's B-cell Program Purchase

Deal News | Mar 20, 2025 | Ropes & Gray

Sanofi, advised by Ropes & Gray, has announced its intention to acquire the bispecific myeloid cell engager program (DR-0201) from Dren Bio. The program aims to address B-cell mediated autoimmune diseases such as lupus, where there is a great need for innovative treatments. The transaction, valued at up to $1.9 billion, involves an upfront payment of $600 million with an additional $1.3 billion contingent on reaching specific developmental and commercialization milestones. Ropes & Gray's team, led by partners specializing in life sciences licensing, M&A, and IP transactions, played a critical role in facilitating this acquisition, which is slated for completion by Q2 2025.

Sectors

  • Biotechnology
  • Pharmaceuticals
  • Legal Services

Geography

  • United States – Ropes & Gray, the legal advisor, is based in the U.S., and the transaction involves a U.S.-based biopharmaceutical entity, Dren Bio.
  • France – Sanofi, the acquiring company, is headquartered in France, marking this as a cross-border acquisition.

Industry

  • Biotechnology – The acquisition pertains to a biopharmaceutical program targeting autoimmune diseases, a key area within the biotechnology sector.
  • Pharmaceuticals – Sanofi, a major pharmaceutical company, is expanding its portfolio to include novel treatments for autoimmune diseases.
  • Legal Services – Ropes & Gray provided legal advisory services for the acquisition, underscoring the role of legal expertise in complex M&A deals.

Financials

  • $600 million – Upfront payment for the acquisition of Dren Bio's DR-0201 program.
  • $1.3 billion – Potential future payments based on achieving certain development and launch milestones.
  • $1.9 billion – Total potential value of the acquisition deal.

Participants

NameRoleTypeDescription
SanofiAcquirerCompanyA leading global pharmaceutical company seeking to expand its immunology portfolio.
Dren BioTarget CompanyCompanyA biotechnology firm focused on developing bispecific antibody-based therapies.
Ropes & GrayLegal AdvisorCompanyA leading law firm providing comprehensive advisory services for the acquisition.
Abigail GregorLife Sciences Licensing PartnerPersonLed the Ropes & Gray team on the licensing aspects of the acquisition.
Matt ByronMergers & Acquisitions PartnerPersonKey partner in the M&A advisory for the acquisition.
Dan FreshmanIP Transaction AssociatePersonPart of the IP advisory team at Ropes & Gray for the acquisition.
Scott PinarchickTax PartnerPersonProvided tax-related advice in the acquisition process.
Renata FerrariEmployment & Benefits PartnerPersonHandled employment and benefits issues in the deal.
Joshua TalicskaIP Transactions CounselPersonCounseled on IP transactions for the acquisition.
Alexandra CharronMergers & Acquisitions AssociatePersonAssisted in M&A aspects of the acquisition.
Giancarlo LeeIP Transactions AssociatePersonProvided IP transactions support in the acquisition.