Montara Therapeutics Secures $3.3 Million Grant for Parkinson's Research

Deal News | May 21, 2025 | SV Health Investors, LLC

Montara Therapeutics, a biotech company focused on developing brain-selective therapies for central nervous system diseases, has been awarded a $3.3 million grant from The Michael J. Fox Foundation for Parkinson’s Research. This non-dilutive funding will support Montara in the development of a next-generation BrainOnly LRRK2 inhibitor, intended to avoid peripheral toxicities associated with current therapies that impact organs such as the lung and kidney. The grant comes as part of MJFF’s strategic approach to advance novel therapeutic approaches targeting LRRK2—an area with significant drug development challenges in Parkinson's disease. As part of the initiative, Montara will also participate in MJFF's LRRK2 Investigative Therapeutics Exchange (LITE) program, which provides resources for advancing LRRK2-targeted therapeutics and involves a collaboration across numerous academic and clinical centers worldwide. Montara's innovative platform strategically combines brain-penetrant drugs with peripheral blockers, aiming to overcome the safety barriers that have historically impeded CNS drug development. The collaboration underscores Montara's role in progressing therapeutic prospects within the Parkinson's disease domain.

Sectors

  • Biotechnology
  • Healthcare
  • Pharmaceutical

Geography

  • United States – Montara Therapeutics is based in San Francisco, California, USA.
  • United Kingdom – The University of Dundee in the UK is a significant player in the LITE program.

Industry

  • Biotechnology – The article discusses Montara Therapeutics, a biotech firm developing novel therapies for neurological diseases.
  • Healthcare – The focus is on developing treatments for Parkinson's disease, impacting the broader healthcare sector.
  • Pharmaceutical – The target development of a new drug for Parkinson’s falls under the pharmaceutical industry.

Financials

  • $3.3 million – Non-dilutive grant awarded to Montara Therapeutics by The Michael J. Fox Foundation.

Participants

NameRoleTypeDescription
Montara TherapeuticsTargetCompanyA biotech firm developing brain-selective therapies for CNS diseases.
The Michael J. Fox Foundation for Parkinson’s ResearchGranterCharityA foundation providing funding and supporting research for Parkinson’s disease.
SV Health Investors, LLCInvestorCompanyA private equity firm investing in healthcare and life sciences.
University of DundeeCollaboratorEducational InstitutionPartaking in the LITE program to foster research collaboration.