Apini raises £1.8m to advance treatment for chronic diseases

Deal News | Jun 11, 2025 | Business Cloud

Apini raises £1.8m to advance treatment for chronic diseases

Apini, a company developing small molecule drug treatments for chronic inflammatory diseases such as Crohn's disease and Ulcerative Colitis, has successfully raised £1.8 million to further its development efforts. The company is a spinout from the University of Manchester and benefits from support by the university's Innovation Factory. The financial backing was provided by Northern Gritstone, a firm that has garnered recognition for its investment activities in the Northern region. Syncona's Slingshot Therapeutics accelerator plays a fundamental role in advancing Apini by harnessing insights from distinguished academic research, with initial financial backing amounting to £12.5 million. The program's development is led by Professor Sam Butterworth, known for creating Tagrisso, a globally utilized anti-cancer drug. This investment aims to facilitate the evolution of Apini into an impactful biotech participant in the life sciences sector, specifically targeting the treatment of inflammatory diseases without immune system suppression.

Sectors

  • Biotechnology
  • Healthcare

Geography

  • United Kingdom – The company Apini, and its investor, Northern Gritstone, are based in the UK, specifically connected to the University of Manchester.

Industry

  • Biotechnology – The article discusses the development of small molecule drugs aimed at treating chronic inflammatory diseases, a key area within the biotech sector.
  • Healthcare – Apini is working on therapeutic solutions for chronic diseases, placing it within the healthcare sector.

Financials

  • £1.8 million – The amount raised by Apini to continue its drug development for chronic inflammatory diseases.
  • £12.5 million – Initial commitment made by Syncona for the creation and running of Slingshot Therapeutics.

Participants

NameRoleTypeDescription
ApiniTarget CompanyCompanyA biotech spinout from the University of Manchester, focusing on developing treatments for chronic inflammatory diseases.
Northern GritstoneInvestorCompanyAn investment firm known for its engagement in Northern UK, and investor in Apini.
SynconaMajor Investor & Accelerator PartnerCompanyAn investment and healthcare company that supports Slingshot Therapeutics, the accelerator assisting Apini.
Slingshot TherapeuticsAcceleratorCompanyAn accelerator built by Syncona to support the development of new therapeutic programs.
University of ManchesterOriginatorCompanyA leading research university where the initial drug development work for Apini was conducted.
Professor Sam ButterworthFounding ScientistPersonA scientist noted for developing Tagrisso, he is leading the research efforts for Apini.