Ambience Healthcare Secures $243 Million Series C Funding
Deal News | Jul 29, 2025 | Raptor Capital Management LP

Ambience Healthcare, an ambient AI platform focused on improving documentation, coding, and clinical documentation integrity (CDI) across health systems, has announced a successful $243 million Series C funding round. Key investors include Oak HC/FT, Andreessen Horowitz, OpenAI Startup Fund, Kleiner Perkins, Optum Ventures, and others. Ambience's AI-driven platform integrates with electronic health records (EHRs) to streamline workflows in various healthcare settings. The investment will enable Ambience to further expand its AI capabilities and enhance its product offerings across the healthcare spectrum. High-profile healthcare institutions such as Cleveland Clinic and UCSF Health are leveraging Ambience's technology to improve documentation accuracy and reduce admnistrative burdens.
Sectors
- Healthcare Technology
- Artificial Intelligence
- Investment and Finance
Geography
- United States – Ambience Healthcare primarily operates in the US, and the article mentions several US health systems and institutions utilizing its platform.
Industry
- Healthcare Technology – The article focuses on Ambience Healthcare and its AI-driven solutions for improving healthcare documentation processes.
- Artificial Intelligence – Ambience Healthcare's core technology revolves around AI, particularly in automating and streamlining healthcare workflows and documentation.
- Investment and Finance – The article discusses a significant Series C funding round led by venture capital firms, indicative of investment trends in the healthcare tech sector.
Financials
- $243 million – The total Series C funding amount raised by Ambience Healthcare to expand its AI platform.
Participants
| Name | Role | Type | Description |
|---|---|---|---|
| Ambience Healthcare | Target company | Company | A leading AI platform that optimizes documentation, coding, and clinical workflows in health systems. |
| Oak HC/FT | Co-lead investor | Company | A venture capital and growth equity firm investing in healthcare information and services companies. |
| Andreessen Horowitz (a16z) | Co-lead investor | Company | A leading venture capital firm investing in tech-driven companies, particularly in the healthcare sector. |
| OpenAI Startup Fund | Existing investor | Company | An investor in AI-enabled ventures, supporting companies pushing AI capabilities. |
| Kleiner Perkins | Existing investor | Company | A venture capital firm that backs bold entrepreneurs building disruptive companies. |
| Optum Ventures | Existing investor | Company | The investment arm dedicated to advancing technology and innovation in healthcare. |
| Frist Cressey Ventures | New investor | Company | A business aiming to improve healthcare through strategic investments. |
| Town Hall Ventures | New investor | Company | An investment firm that partners with companies delivering critical healthcare solutions. |
| Smash Capital | New investor | Company | An investment firm focusing on companies with innovative technology in the consumer landscape. |
| Georgian | New investor | Company | A growth-stage investment firm -- to further propel AI application developments. |
| Founders Circle Capital | New investor | Company | A large-support company helping late-stage companies scale. |
| Cleveland Clinic | Client | Company | A high-profile US health system using Ambience's AI documentation technology. |
| UCSF Health | Client | Company | A prominent healthcare provider adopting Ambience for improved administrative efficiency. |
| Houston Methodist | Client | Company | A leading health system in the US utilizing Ambience software for workflow optimization. |
| Memorial Hermann | Client | Company | Another major American healthcare institution employing Ambience tech for better care administration. |
| Vig Chandramouli | Partner at Oak HC/FT | Person | A partner at Oak HC/FT, one of the co-lead investors in Ambience Healthcare. |
| Michael Ng | CEO of Ambience Healthcare | Person | The Chief Executive Officer of Ambience Healthcare, working on transforming clinical documentation processes. |
| Julie Yoo | General Partner at Andreessen Horowitz | Person | A general partner at Andreessen Horowitz, an investor witnessing substantial impact from Ambience’s platform. |